Ralph.... I became "postmenopausal" literally in a few minutes in 1989, 'cause I had a hysterectomy. My OB/GYN put me on estrogen replacement therapy immediately. I'd already had PD about 12 or 13 years by then. I've used the estrogen patches with no problems. However, there's been a few times when I ran out of patches right when I was supposed to change to a fresh one, and THEN I got "Parkie-ish." Since that was real good incentive for me to get in my car and high-tail it over to the drugstore and pick up my prescription, I was feeling back to my old self (whatever THAT is to a PWP!) about an hour after putting on the fresh patch. Sooo... I feel that estrogen hasn't adversely affected the PD symptoms, unless I should get lazy and run out of patches (and I try VERY hard not to do that any more!). Barb Mallut [log in to unmask] ---------- From: Parkinson's Information Exchange on behalf of Ralph Reichert Sent: Monday, October 06, 1997 5:04 PM To: Multiple recipients of list PARKINSN Subject: Estrogen Replacement Therapy (ERT) and PD I've read that ERT can be "antidopaminergic" and make PD worse in a postmenopausal woman. Has anyone any experience with ERT and PD? Does anyone know more about this subject? I'd be grateful for information. Ralph