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Prozac I believe has a relative contraindication with selegeline. That is it is not "forbidden" as a combination but theoretically- and in some relatively rare cases the combination caN CAUSE "SERATONIN SYNDROME". Since selegeline is a selective mao inhibitor rather than a general MAO inhibitor the risk of interaction is much less at the doses used in PD. (5-10 mg/day). If the depression is a significant problem many MD's will weigh the risk of the combination vs the risk of the depression and prescribe the combination- with caution. Charlie Arthur Hirsch wrote: > > At 07:06 PM 10/12/97 -0400, Emily Rosenthal wrote: > >3) I believe I read somewhere that prozac is contra-indicated with selegeline > >- some bad side effects. But my mind is worse than my mother's these days - > >can anyone confirm this? > > > >emily cg/Mom 76/3 months ([log in to unmask]) > > > I just returned from hospital for a hernia repair this past week. I > emphasized to everybody I met that demerol was contraindicated, since I was > taking eldepryl, and I got a red wristband with "Demerol" written on it in > bold letters, indicating that I should not be given demerol. They also > added "Prozac" on the tag, but they said that they had no feeling that > there would be any need for a drug like prozac, so it was academic. > > Maybe I've overlooked it, but I've seen lots of data on prozac here on this > list, and its contraindication with selegeline does not seem to have been > one of them. So I too am now curious. Is this a new development? > > Art > > Arthur Hirsch [] [log in to unmask] [] Lewisville, TX > ____________________________________________ > > Always Remember This: > Happiness Is Right, So Choose Happiness > ____________________________________________ -- CHARLES T. MEYER, M.D. Middleton, WI [log in to unmask]