Rosemary Paul wrote: > > Peter - I tried to send this message to you yesterday via the list and > then to you and both came back. However I think I am straightened out > now with the list. Had different id in my signature and e-mail addresses. > I am from the USA and have been in a study for tolcapone/tasmar since > Sept 4 at the Univ. of Kansas Med Center under the direction of Dr. Wm. > Koller, head of the US Tolcapone study. To start this I had a month > washout period from Permax. Added to that I was taking 6 25/100 > sinamets, one eldepyrl and one zoloft. The biggest problem I had at > first was increased dys that was disabling at times. I still work full > time nd this was a problem. > However since I reduced the sinamet to 1 25/100 a day along with three > 100 mg. tasmar, one eldepryl and one zoloft - the dys has all but > disappeared. I was diagnosed with PD 12 years ago. At that time I was > in the study for eldepryl and feel that it delayed the progress of my PD > (even tho that was not proven). Anne Rutherford mentionedthat she had to > quit tasmar because of side effects but I have not noticed any but the dys. > Two years ago I started falling but not every day - more like every 3 or > 4 months so that is not caused by tasmar. Another person I heard from in > Denmark had to quit because of blood pressure problems. My energy has > not increased. I take my first meds at 6:30 am and last dose at 6:30 pm. > Eliz. Butler said she had met you at the oz convention and that you had > had palloidal (sp) surgery. > Lets keep in touch and I too welcome any comments, ideas or > experiences with tolcapone. > Rosemary > ***************************************************** > Rosemary Paul > [log in to unmask] > Community Services x3919 > *****************************************************Rosemary - Thanks for your reply on tolcapone. Just one question - why did you stop taking Permax - I thought you could take tolcapone with all existing meds. Also 5% of people suffer diarrhea from Tolcapone and I think this was Anne's problem (I hope she doesn't mind me mentioning that) but I know that constipation is a side effect of Bromocriptine and as Permax is from the same family of drugs I was wondering if one of these drugs could counteract the diahrrea problem - just a thought. Yes I did have deep brain stimulation - am still sorting out frequency levels at this stage - would not recommend it until more research is done. Kind regards Peter Dawkins