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Hi, Marcia, Jim 63/14 has been on Mirapex for 8 weeks now. Due to some hallucination problems I started his therapy MUCH slower than the norm. I increased the dosage MUCH slower than suggested i. e. 0.125mg every 3 days. I flet that any adverse reaction wuld not be so severe and I could back away much quicker. I work all day, so I could not have Jim having a bad day and my not be here. Jim is up to 3.0 mg per day. His drooling is verturlly gone, his off times are very much fewer, his cognitive skills not much better, and speech is no better. But his overall abilities are better including his sleep. God willing we will continue. Hope this helps. Arlene CG