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Rosemary Paul wrote: > > Rae I too have been wondering about the silemce on tolcapone. Is it > because it is not approved here so not many in US are taking it. > I am 68/12, have been on tolcapone 6 weeks. Saw my neuro yesterday. He > want me to increase to the 200mg tablets 3x a day - I have been able to > cutthe sinamet I.m taking to 1 and 1/2 25/100 instead of the 6-8 I was > taking. I notice a slow period bradykinesia in afternoon hence the > increase in tolcapone to perhaps cause more sinamet to be accepted by the > brain. > On the down side last week I developed the side effect of diahrhea (sp), > flatulence etc you describe. This was three weeks after starting tolcapone. > Dr. Koller said this is the norm after u take it for awhile. He had no > explanation - said the company had spent a lot of money researching it > but no answer so far. > I will have to decide if the benefits outweigh this inconvenience (g) - > so far yes. > Would like to hear from more. BTW I got your message 4times so it did go > thru to me at least. > > ***************************************************** > Rosemary Paul > [log in to unmask] > Community Services x3919 > *****************************************************Rosemary - I tried to reply to your Tasmar msg last week but think I was unsuccessful. I queried why you stopped taking Permax as I understood you could take Tasmar with all existing meds. Also I know a side effect of Parlodel is constipation and as Permax is in the same drug family as Parlodel was wondering if this might counterract the diarrhea problem - just a thought. Yes I did have deep brain stimulation - am still trying to sort out frequency levels - would not recommend it until further research is done. Kind regards Peter Dawkins