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Although I had never thought of the two at the same time--I had just fallen asleep and then the leg cramps and foot cramps hit me! I jumped out of bed and tried to walk them off! I don't know if that is best or not. I finally took a K-dur(potassium supplement) and a sinemet 25/100. I am afraid to lay down again I am afraid those cramps will start. So--is anyone of you who are up now experiencing the same thing? Carol Gray [log in to unmask]