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Charlie Meyer wrote: > Brian, > > I think the jury is still out. It makes sense to me that given an > unknown one should try agonists first but not delay l-dopa if there is > significant disability. Do you have data that there is no difference in > the onset of dyskinesia regardless of when someone starts l-dopa? > > Charlie Brian, I would like to add my voice to Charlie's, particularily as every neurologist I speak with belongs to the "start levodopa as late as possible" school of thought. It is entirely possible that your point of view will prove to be correct but as Charlie remarks the jury is still out. Whilst the debate is in progress refering to one side of it as "that nonsense" introduces an emotional element which is less than helpfull. I was also surprised that you, of all people, should introduce it, especially considering your recent complaint that the selegiline debate became to personal. I look forward to reading your data reference onset times for dyskinesia. Dennis. ************************************************* Dennis Greene 48/10 [log in to unmask] http://members.networx.net.au/~dennisg/ **************************************************