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Camilla, Going slow especially with Peter's history of adverse response to other new medications (which we have all followed both with horror and sympathy)- makes perfect sense. It also makes sense that the decrease in sinemet would cause worsening of his PD especially with the low dose of the agonist Requip. SLOW is the name of the game at this point (I guess it is the operative word for all of us PWP on a daily basis). We are all out here rooting for you and Peter and pray that the Requip gives him some relief. Good luck. Charlie Camilla Flintermann wrote: > > Progress report on introducing ReQuip: > Peter is taking ONE pill a day, which is 1/3 the recommended dosage from > the manufacturer--but the neuros felt it should be very gradual because > he had such a bad reaction to Mirapex. > After 1 week, he did have an episode of hallucination in the night, but > not a horrifying one. I called the clinic and they at once said to cut his > Sinemet, so that he takes only 1/2 as much for the 7AM and 1PM doses. > He has so far not had more hallucinations, but we are noticing an increase > in off times, which I assume is due to LESS Sinemet and not yey enough > ReQuip to be helpful. Does this sound sensible? I hope and believe that as > he is able to increase the ReQuip, motor function will improve. We are both > very anxious NOT to repeat the paranoid episode he had with Mirapex when Sineme > t had NOT been reduced. > Will keep you posted! > > Camilla Flintermann, CG for Peter, 79/8, Oxford,Ohio > [log in to unmask] > * * * * * * * * * * * * * * > "Ask me about the CARE list for PD caregivers!" > * * * * * * * * * * * * * * -- CHARLES T. MEYER, M.D. Middleton, WI [log in to unmask]