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Barb, I haven't had the experience of going off Mirapex, but yesterday I didn't take it for five hours (old dementia kicking in) and suffered for it miserably last night: anxiety attack, and pains similar to those you described. Makes you think twice about giving it up. I'm scheduled to start tolcapone as soon as it's approved. After your experience (and mine) I think I'll try to add it to Mirapex instead of using it as a replacement. Right now I'm fighting the same battle as you were with the dyskinesias. I can't cut down on the sinemet because I take the lowest dose CR's, and if I prolong the intervals between doses, I go "off." For the past two days I've been cutting up the Mirapex, and that seems to help. Good luck - with your medicine and your move. Pat