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Barb asks: > >Has anyone here, in going off Mirapex (for whatever reason) experienced >withdrawal symptoms/problems of any kind that you can attribute directly TO >going off the Mirapex? > I went off Mirapex by titrating down from 3x3 per day to 2x3 the next day and 1x3 the next then ground zero. Like jumping out of a plane. Mirapex had caused me so many mood problems that as the fog cleared I felt like I had been given my life back! Whew! I looked back on the ordeal with disbelief. I did find immediately however what parlodel and mirapex had been doing for me as I was finally using no agonist, and had to bump my sinemet by probably 30-40% or so. I'm still trying to get used to taking my meds BEFORE I go off, since now off means off. No more graceful slide into the goo, the goo turns to cement in about 10 minutes. I have decided to pass on all dopamine agonists for the moment and sleep for a few months. I have started on NADH again, as that always has an agonist-type effect on me, and I have overcome the sleep problems that it caused initially. Kathie Tollifson [log in to unmask] 47/9