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hi linda you wrote: >my father is taking 1/2mg 3x a day of Mirapex (for 3 months) and >25/100 3x a day of Sinement (for 3 weeks). >He is experiencing a lot of leg weakness, and the inability to walk, >could this be too much, or what could be causing this problem? has he only been on sinemet for three weeks? if so, this reminds me a bit of steve and ellen peck's problem with steve having been started on sinemet at too fast a rate is he having any other problems besides leg weakness? is he taking any other medications? what were his symptoms pre-mirapex? and then pre-sinemet? your cyber-sis in sleuthing janet janet [log in to unmask]