My dad is on Mirapex ... in general he's doing much better than on the Sinemet (which has now been eliminated). He was "sicker than a dog" on that now at least he's alert and functional though his walking isn't what it used to be pre-PD. He's at 0.625 mg in the am (9:30) ... 0.5 at noon and 0.5 at dinner (about 6). He's tried going to the higher dose - his N wants him at 1mg 3x - but he feels dizzy and light headed at any higher dose than he's taking now. But now I'm wondering if he's not taking them too close together ... the Dr said with meals and thats when my dad eats B-L-D (retirees don't have to get up and eat at un-Godly hours) ... but it really puts his lunch dose at only 3 hours after his morning one - maybe its a bit of an OD those few hours. Another related ? is that he uses Xalatan drops in his eys for Glaucoma. The info packet with that says it can cause dizziness/nausea - but he's been on that for over a year with no problem ... maybe something between that and high dose of Mirapex ? any comments suggestions ? Donna (daughter of PD dad 74 dg 1/97 Mirapex) ------------------------------------------------------------------------------ - Donna Bassolino-Klimas, Ph.D. Bristol Myers Squibb Pharma. Res. Inst. Department of Macromolecular Structure P.O. Box 4000 Room H3812 Princeton, N.J. 08543 4000 (609) 252 4413 INTERNET: [log in to unmask] ------------------------------------------------------------------------------