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Lanier, Amitriptyline (Elavil) is an antidepressant which was one of the early drugs in this group to go on the market. It was effective as an anti-depressant but a large percentage of patients that took it developed side effects some of which were as uncomfortable as the illness that it was being used to treat. Doses of 150-200 mg / day were not uncommon and at times doses given would exceed 300 mg/day. So as far as risk goes an increased dose should not be a problem. However, if side effects are a problem another antidepressant trazodone can be used for the same purpose with a decreased side effect profile at low doses. Charlie p. l. maddux wrote: > > Hi list friends, I have been mostly lurking, but have a situation I > would like some comment on. I have had a tremor for two years now and am > taking no pd medications, but I have had long term problems with poor > quality of sleep. Maybe of course caused by the oncomming pd. It got so > bad I told my neuro about it and he prescribed Elavil 10 mg. That helped > a lot for two weeks, then the DR put me on 25mg, That helped a lot for 2 > months but is not helping much now, I know he will increase the dose > again, but how much further can I ;go, The dose now is causing two side > effects,, blurred vision and constipation. So now I have three problems > If I continue increasing the dose, won't I just continue to have more > severe side effects > > Lanier Maddux Chattanooga, Tn. > ([log in to unmask]). -- CHARLES T. MEYER, M.D. Middleton, WI [log in to unmask]