I must take a moment to express my total elation at a most welcome turn of events with my PD. I MENTION THIS IN THE HOPE THAT MAYBE SOMEONE ELSE WILL (ALSO) FIND SOME RELIEF. This is a long posting purposely done to detail SYMMETREL. For those who dont know or remember, my PD settled in my legs. It was at a point where I was 90% dependent. I couldnt stand up alone, my balance was terrible; my thigh muscle hurt and I litterally felt like a veg. I had a knock down meeting with my PD specialist neuro and he was at the end of his rope. My meds were working fine (i.e. any more and I went over the edge)(any less and I was a total mess). I have no tremor and no dyskenesias. My legs just didnt want to move and the left one hurt all the time. (I had a left pallidotomy so the right side was better) The neuro spoke about how now that we know more about Pallidotomies, we realize they are'nt long lasting. In fact about 2-3 years before the PD progresses past the results of the op. Since further surgery was not an option for me now and any of the new meds were not for my symptoms, he was lost how to help. Finally he come up with a suggestion for a med I never took. Last Monday I was a basket case in his office. He suggested to try an older medd..SYMMETREL. Start with two a day for a week then increase one a week up to four if needed. With that I also began to take two QUININE tabs a day. Fellow Parkies, Ive had this disease for 15 years and have NEVER had more instant positive results from any medicine. My strength has returned to "normal", the pain is 95% gone, the stiffness that prevented me from moving as become a non-factor and I can now litterally march around sometimes with my cane AND we are finally getting a night sleep. Folks, I only hope this message may help someone else. Maybe it wont last another day, but I can only say THANK YOU G.D for giving me a week of new life. Does anyone else take SYMMETREL (AMANTADINE HCI) 100MG. and if so what symptom is it supposed to relieve. Sorry for the long post....Im excited and hope this info may help someone else. Joyce