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HI Emily, Compazine is used primarily to control nausea and vomiting. It is however a "phenothiazine". Other drugs in that class include the antipsychotics like chloropromazine(Thorazine), Trifluoperizene (Stelazine) and others. All these drugs block the effect of dopamine. They can cause what are referred to extrapyramidal side effects while someone is taking them. These are symptoms PWP experience. There is no evidence- that I am aware of- that use of these drugs predisposes one to develop PD. However someone with early PD is much more likely to experience the side effects while the taking the drugs. Compazine definitely should not be used by PWP except in very rare cases. Charlie Emily Rosenthal wrote: > > I've heard compazine is bad for or possible cause factor in pd. I'd be > interested in more information anyone has. My mom took compazine way too > regularly for many years. Her neuro didn't get too excited by this info, but > did suggest she not take it now. I don't know if my motive in asking is to > find blame, reassurance, or just information. Thanks for your input. > > emily ([log in to unmask]) for mom 76/4 months dx, now saying may be Park. Plus > nyc -- CHARLES T. MEYER, M.D. Middleton, WI [log in to unmask]