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^^^^^^GREETINGS FROM^^^^^^^^^^ Ivan Suzman 47/10 [log in to unmask] Portland, Maine land of lighthouses deg. F *********************************************************** On Fri, 21 Nov 1997 01:41:57 -0500 [log in to unmask] writes: >According to my neuro.....mirapex and sinemet can both lower blood >pressure......perhaps you are just overmedicated on the combo or only >the >mirapex........try reducing the mirapex. >Rita > Hi Rita, ThANK YOU for your suggestion.. I am down from 5 to only 1 Mirapex (0.125 mg.)/ day. It is taken at 12:30 am, to see if that helps extend my nighttime "on" period, and possibly helps me to sleep by avoiding end-of-dose dystonia that has been very painful.. I cannot take Mirapex, even in this tiny dosage, during the day, without losing alertness. Perhaps I am an example of ultra-sensitivity to agonists, since even the tiniest Permax dose made me disoriented and drowsy, and Parlodel also made me drowsy, while knocking down my blood pressure. My local neuro thinks I may have to give up entirely on Mirapex, and try Ropinerole(Requip).. I am watching the Dale Severance reports and others for side-effects already troubling me with Mirapex. What I wonder is--is it Parkinson's or is it the agonists or both, that lower my Blood Pressure? IVAN