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Day 6 REQUIP set back 4 AM woke up more on than off. Read list messages for one hour and went back to bed and fell asleep for three more hours. This is something I almost never can do. Took .50 mg requip and 1 sinemet 25/100 about 4:30 AM when I had no intentions of going back to sleep 8 AM woke up with a bad headache and half on half off took 1 sinemet Though out the day the bad headache has continued. As I compose this article it is 5:50 PM and my on and off state has remained the same. I have remained half on and half off all day. My left foot has been turning in and toes curling under for first time since I started requip. Left arm tremors I have had several occasions in fact almost all day What a difference from yesterday. I had almost decided to stop increasing requip as I was satisfied with extending my off periods from 2 ¾ hours to 4 ½ hours. I wonder if I am waiting too long to take next dose of sinemet. I have been waiting till I started to go off to measure the effective ness of requip. Going to take sinemet at 4 hours 15 min intervals for a few days. Also getting to be major concern is pulse rate now at 48/min. Is my headache related to slow heart beat??? 11 AM took second dose of the day of requip .50mg and I sinemet. Half off half on stuck in neutral. 1: 30 TOOK SINEMET. Trapped at Mall in off condition and felt needed booster to drive home. Not much help 6; PM taking sinemet as still half and half. I may have taken a sinemet about 3 PM I do not remember fell a sleep about three for 2 hour nap. Dale Severance