This is a multi-part message in MIME format.
--------------E407C5C85A8345AFE2A93B9C
Content-Type: text/plain; charset=us-ascii
Content-Transfer-Encoding: 7bit
http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9056710&form=6&db=m&Dopt=b
--------------E407C5C85A8345AFE2A93B9C
Content-Type: text/html; charset=iso-8859-1; name="query"
Content-Transfer-Encoding: quoted-printable
Content-Disposition: inline; filename="query"
Content-Base: "http://www.ncbi.nlm.nih.gov/htbin-post
/Entrez/query?uid=9056710&form=6&db
=m&Dopt=b"
<html>
<head>
<TITLE>PubMed medline query</TITLE>
</head>
<body bgcolor=3D"#f0f0f0" text=3D"#000000"
link=3D"#0000f0" vlink=3D"#6000b0" alink=3D"#f00000">
<Bass href=3D"http://www.ncbi.nlm.nih.gov">
<!-- machine jupiter -->
<a href=3D"/htbin-post/PubMed/imagemap/PubMed/maps/pubmed_query.map"> =
<img width=3D510 height=3D22 border=3D0 ismap src=3D"/PMGifs/TitleBar/TBa=
r_PubMed-med-query.gif"
alt=3D"Entrez medline Query"></a><P> =
<FORM METHOD=3DPOST ACTION=3D/htbin-post/Entrez/query?db=3Dm_x>
<INPUT TYPE=3D"hidden" NAME=3D"doclistpage" VALUE=3D"1">
<strong>Other Formats:</strong> <a href=3D"/cgi-bin/Entrez/referer?/htbin=
-post/Entrez/query%3fdb=3Dm&form=3D6&uid=3D9056710&Dopt=3Dr"><img src=3D"=
/PMGifs/Toolbar/citation.gif" border=3D0 align=3Dtop alt=3D"[Citation For=
mat]"></a>
<a href=3D"/cgi-bin/Entrez/referer?/htbin-post/Entrez/query%3fdb=3Dm&form=
=3D6&uid=3D9056710&Dopt=3Dl"><img src=3D"/PMGifs/Toolbar/medline.gif" bor=
der=3D0 align=3Dtop alt=3D"[MEDLINE Format]"></a>
<BR>
<strong>Links:</strong> <a href=3D"/cgi-bin/Entrez/referer?/htbin-post/En=
trez/query%3fdb=3Dm&form=3D6&uid=3D9056710&Dopt=3Dm"><img src=3D"/PMGifs/=
Toolbar/relart.gif" border=3D0 align=3Dtop alt=3D"[113 medline neighbors]=
"></a>
<P><em>Annu Rev Neurosci</em> 1997;<strong>20:</strong>125-156 <P><h2>Th=
e role of vesicular transport proteins in synaptic transmission and neura=
l degeneration.</h2>
<P><h4>Liu Y, Edwards RH</h4>
<P>Classical neurotransmitters are synthesized in the cytoplasm, so they =
require transport into secretory vesicles for regulated exocytotic releas=
e. Previous work has identified distinct vesicular transport activities f=
or the different classical transmitters, and all depend on the H+-electro=
chemical gradient across the vesicle membrane but differ in the extent to=
which they rely on the chemical and electrical components of this gradie=
nt. Drugs that interfere with vesicular amine transport have implicated t=
his activity in psychiatric disease. Selection for a cDNA encoding vesicu=
lar amine transport in the neurotoxin MPP+ also implicates the activity i=
n Parkinson's disease. Molecular cloning of vesicular monoamine transport=
ers shows sequence similarity to bacterial antibiotic resistance proteins=
, supporting a role for transport in detoxification and defining a novel =
mammalian gene family that now also includes a transporter for acetylchol=
ine. Current work focuses on the mechanism of transport and the role that=
regulation of activity and its subcellular localization have in transmit=
ter release, behavior, and neural degeneration.
<P>Publication Types:<BR>
<UL>
<LI>Review
<LI>Review, academic
</UL>
<P>PMID: 9056710, UI: 97209410
<HR SIZE=3D5 NOSHADE><P>
</FORM>
<FORM METHOD=3DPOST ACTION=3D/htbin-post/Entrez/query?db=3Dm_w>
<INPUT TYPE=3Dhidden NAME=3Dform VALUE=3D6>
<INPUT TYPE=3Dhidden NAME=3Ddb VALUE=3Dm>
<INPUT TYPE=3Dhidden NAME=3Ddopt VALUE=3Db>
<INPUT TYPE=3Dhidden NAME=3Ddispmax VALUE=3D1>
<INPUT TYPE=3Dhidden NAME=3Duidstring VALUE=3D"9056710">
<INPUT TYPE=3Dsubmit VALUE=3D"Save"> the above report in =
<SELECT NAME=3D"save">
<OPTION>Macintosh
<OPTION>PC
<OPTION>UNIX
</SELECT>
<SELECT NAME=3D"savehow">
<OPTION>Text
<OPTION>HTML
</SELECT>
format.
</FORM><HR SIZE=3D5 NOSHADE>
</html>
--------------E407C5C85A8345AFE2A93B9C--
