This is a multi-part message in MIME format. --------------0A187DDFC3B1DD9B7A6390BE Content-Type: text/plain; charset=us-ascii Content-Transfer-Encoding: 7bit Hi Jim, I was on Permax, .25mg 3x a day, before switching to Mirapex. I cut down over three weeks. My offs were more severe but not more frequent. I had no other problems. Permax made me very constipated. I have not had that problem with Mirapex. I am now on .5mg Mirapex 3x a day. I have had a little improvement in extending my on times, but nothing dramatic. Regards, Bruce --------------0A187DDFC3B1DD9B7A6390BE Content-Type: text/x-vcard; charset=us-ascii; name="vcard.vcf" Content-Transfer-Encoding: 7bit Content-Description: Card for Bruce Hollenbeck Content-Disposition: attachment; filename="vcard.vcf" begin: vcard fn: Bruce Hollenbeck n: ;Bruce Hollenbeck email;internet: [log in to unmask] x-mozilla-cpt: ;0 x-mozilla-html: FALSE version: 2.1 end: vcard --------------0A187DDFC3B1DD9B7A6390BE--