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Philip Connors wrote: > She a just added, a few weeks ago, Buspar (for depression) to her med= s. > She is not reacting well to it. Very tired, perhaps more freezing epi= sodes. > She is taking Sinemet (reg, CR, and Liquid),Eldepryl, Permax, Prozac, > Diazepam, plus a variety of vitamins. Dear Phil, Buspar is among the drugs to be used with caution in PD. Here is an additive adverse reactions report for the medications your wife is taking. Perhaps it may be of some help. I note five of the meds may cause drowsiness and two may cause fatigue -- perhaps the additive effect is what your wife is experiencing. --------------- Additive adverse reactions report for the following 6 medications: =9ABuspirone (BuSpar=AE) =9ADiazepam (Valium=AE, Valrelease=99, Dizac=99) =9AFluoxetine (Prozac=AE) =9ALevodopa; Carbidopa (Sinemet=AE) =9APergolide (Permax=AE) =9ASelegiline (Eldepryl=AE) 5 of these drugs may cause: =95dizziness (buspirone; diazepam; fluoxetine; pergolide; selegiline) =95drowsiness (buspirone; diazepam; fluoxetine; pergolide; selegiline) =95nausea/vomiting (buspirone; fluoxetine; levodopa/carbidopa; pergolide;= selegiline) 4 of these drugs may cause: =95anxiety (diazepam; fluoxetine; pergolide; selegiline) =95dystonia (fluoxetine; levodopa/carbidopa; pergolide; selegiline) =95headache (buspirone; diazepam; fluoxetine; selegiline) =95insomnia (diazepam; fluoxetine; pergolide; selegiline) =95orthostatic hypotension (fluoxetine; levodopa/carbidopa; pergolide; selegiline) =95tremor (buspirone; diazepam; fluoxetine; levodopa/carbidopa) =95weight loss (fluoxetine; levodopa/carbidopa; pergolide; selegiline) 3 of these drugs may cause: =95akathisia (fluoxetine; pergolide; selegiline) =95anorexia (fluoxetine; levodopa/carbidopa; selegiline) =95confusion (buspirone; diazepam; selegiline) =95diaphoresis (buspirone; fluoxetine; selegiline) =95diarrhea (fluoxetine; pergolide; selegiline) =95hypertension (levodopa/carbidopa; pergolide; selegiline) =95palpitations (fluoxetine; pergolide; selegiline) =95syncope (diazepam; pergolide; selegiline) =95xerostomia (fluoxetine; pergolide; selegiline) 2 of these drugs may cause: =95abdominal pain (pergolide; selegiline) =95agitation (fluoxetine; selegiline) =95angina (fluoxetine; selegiline) =95ataxia (diazepam; levodopa/carbidopa) =95blurred vision (buspirone; fluoxetine) =95constipation (pergolide; selegiline) =95depression (diazepam; selegiline) =95dyspepsia (fluoxetine; pergolide) =95dyspnea (fluoxetine; pergolide) =95fatigue (diazepam; fluoxetine) =95fever (pergolide; selegiline) =95hallucinations (pergolide; selegiline) =95hypotension (diazepam; pergolide) =95involuntary movements (levodopa/carbidopa; pergolide) =95mania (diazepam; fluoxetine) =95myalgia (buspirone; pergolide) =95nasal congestion (buspirone; fluoxetine) =95nightmares (buspirone; diazepam) =95pain (fluoxetine; pergolide) =95paresthesias (buspirone; selegiline) =95psychosis (levodopa/carbidopa; pergolide) =95restlessness (buspirone; diazepam) =95sinus bradycardia (fluoxetine; selegiline) =95tinnitus (buspirone; selegiline) =95urinary retention (levodopa/carbidopa; selegiline) =95weakness (buspirone; pergolide) =95withdrawal (diazepam; pergolide) 1 of these drugs may cause: =95acne (fluoxetine) =95alopecia (fluoxetine) =95anemia (fluoxetine) =95apnea (diazepam) =95back pain (pergolide) =95bronchospasm (selegiline) =95cardiac arrest (diazepam) =95CNS hemorrhage (pergolide) =95contact dermatitis (fluoxetine) =95cough (fluoxetine) =95diplopia (pergolide) =95dysgeusia (selegiline) =95dysphagia (selegiline) =95ejaculation dysfunction (fluoxetine) =95euphoria (diazepam) =95flushing (levodopa/carbidopa) =95GI bleeding (selegiline) =95hot flashes (fluoxetine) =95hyperglycemia (fluoxetine) =95hyperventilation (levodopa/carbidopa) =95hypoglycemia (fluoxetine) =95hyponatremia (fluoxetine) =95hypoosmolarity (fluoxetine) =95hypothyroidism (fluoxetine) =95impotence (fluoxetine) =95infection (fluoxetine) =95interstitial nephritis (diazepam) =95leukopenia (levodopa/carbidopa) =95libido decrease (fluoxetine) =95maculopapular rash (fluoxetine) =95mood lability (selegiline) =95mydriasis (selegiline) =95myocardial infarction (pergolide) =95neuroleptic malignant syndrome (levodopa/carbidopa) =95orgasm dysfunction (fluoxetine) =95peripheral edema (selegiline) =95pharyngitis (fluoxetine) =95polyuria (levodopa/carbidopa) =95prostatic hypertrophy (selegiline) =95pruritus (fluoxetine) =95respiratory depression (diazepam) =95rhinitis (pergolide) =95seizures (fluoxetine) =95SIADH (fluoxetine) =95sinus tachycardia (selegiline) =95sinusitis (fluoxetine) =95suicidal ideation (fluoxetine) =95tardive dyskinesia (selegiline) =95urinary incontinence (levodopa/carbidopa) =95urticaria (fluoxetine) =95vertigo (diazepam) =95visual impairment (fluoxetine) =95weight gain (pergolide) =95xerosis (fluoxetine) -- = Kathrynne Holden, MS, RD Editor-in-Chief, "Spotlight on Food--nutrition news for people 60-plus" http://www.fortnet.org/~fivstar and NUTRITION TOPICS copy-ready handouts http://www.dietetics.com/class/fivstar/ Tel: 970-493-6532 Fax: 970-493-6538