Hello George: You wrote- >>> George Campbell <[log in to unmask]> 12/05/97 12:17am >>> >>>I have to get a root canal. What pain medications and antibiotics can be used with the following drugs? Demadex-20 mg Potassium-10 meq Eldepryl-5 mg Sinemet-25mg/100 x3 Verapamil-240 mg Norvasc-10 mg allopurinol-300 mg study drug possibly pramipexole twice daily<<< George: Local anesthisa is not ruled out for PD patients getting dental work. Be aware that the pain killer Demerol has been reported to cause an interaction with Eldepryl (selegiline) in rare cases. Dentists require full disclosure by the PWP of all the PD medications and then they should consult with the neurologist to get medical clearance before major work, such as root canal. The American Parkinson Disease Association in NYC publishes a list of contraindicated drugs for PWPs. Call 1-800-223-2732. Good luck! Stephan 53/7