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Day 16 Requip diary December 7 , 1997 This was one of those days when I fell asleep at 8 PM while watching Syracuse University Basketball team play Boston College Slept to 1:30 AM and have been up all night since. I woke up on at 1:30 AM took 1 sinemet but no requip and the on period lasted till 4:30 AM. At 4:30 AM took 1 mg of requip and sinemet and remained off for 1 hour. At 5:30 AM I was back on again At 9:15 AM still on but going to take regular medicines and not wait for off period to hit. Note 3 ¾ hours and still on compared to 2 ¾ before started requip. I had a short spell of toes curling and arm shaking during the 4:30 AM off period. Taking 2.0 mg of requip, 25/100 sinemet and 5 mg of elderpyrl. At about 1 PM going to take 2.50 requip goooiiinnnggg up in mg by .50 today and tomorrow if no problems. Changed plans Took 25/100 every 3 hours with 1 mg of requip AT THE SAME TIME thus 8 mg of requip during last 24 hours. Very little time off during this trial period other than 4:30 AM off period. Definitely feeling better. Dale