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> He is taking John off >of Senemet and putting him on Requip. I understood the instructions to be >decrease the Senemet to 1 25/100 tab Senemet 2X a day for 2 weeks. >Decrease Senemet again to 1/2 25/100 tab 2X a day for two weeks. Then >begin Requip as directed on the introductory package: 1 0.25 mg tab 3X day >for one week and so on. I have seen here on this list that people are >taking the two medications at the same time decreasing one and increasing >the other. Is that the correct way? Betty and John-- it's hard to say what the "correct "way is to start REQuip, or any other med--partly because all PWPs are different in how they react to the meds, and partly because no 2 neuros seem to do it exactly the same (see reason #1 ) Is that what all of you have done? There have been a variety of ways of introducing ReQuip mentioned on the lists. InPeter's case, he was told to begin at about 1/3 the rate of increase that was recommended by the mfgr. because he had had serious problems with hallucination on Mirapex. His Sinemet was reduced by one 10/100 a day when he had a milder hallucination at the end of the first week on ReQuip, and that has worked well. We are now starting his 7th week on ReQuip, and he is just now increasing to 2 tabs (of .25mg) 3 X a day. Some folks have gione at the suggested rate, others even faster! It has been said by some that one should stick with it for at least 6 weeks (of the regular dosages) before deciding it won't help. You may not have misunderstood --that may just be his/her way of operating. But don't hesitate to ASK if you have questions or problems--that what you're paying for! Second, have any of you experienced psychological problems when you >started decreasing the Senemet? In Peter's case, no. I should add he is depressed, but this isn't related to the Sinemet reduction. Perhaops you need to be more specific, here or on CARE, about the kind of problems you mean? Hope this, and other replies you will no doubt get, will help. >Betty >[log in to unmask] Camilla Flintermann, CG for Peter 79/8 Oxford, OH [log in to unmask] * * * * * * * * * * * * * * * * * * Ask me about the CARE list for* * Parkinson's caregivers ! * * * * * * * * * * * * * * * * * *