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Yesterday I forgot to take my mid-day dose of meds. I didn't hit the wall that I had been every 4 hours. Forgetting to take meds on time used to be a "problem" for me but I haven't experienced that for three months. In fact it was end dose wearing off that prompted me to try Requip. I'm taking 4 mg Requip &50/200 Sinemet CR 3 times a day,.5mg Permax am and PM, .5 mg eldryprel am and noon. Quite an improvement from 2 weeks ago when I was 2hrs on and 2hrs off. That was when I was at 2 mg Requip &50/200 Sinemet CR 3 times a day, .5 mg eldryprel am and noon, and had weaned off permax gradually over 3 weeks while building up Requip. Getting off Permax was terrible. Aren't drugs Wonderful when they work!!!! -----Original Message----- From: DaleS99846 <[log in to unmask]> To: Multiple recipients of list PARKINSN <[log in to unmask]> Date: Saturday, December 06, 1997 10:54 PM Subject: 12/5/97 Day 14 Requip diary by DALE sEVERANCE Day 14 requip 12/5/97 5 AM awoke & took 1.25 mg of requip, 25/100 sinemet and 5mg of elderpyrl I woke up on which lasted till 7:15 AM and went suddenly off 8 AM took 1 sinemet still off 11 AM apt. with Dr. Perez He decided I was not getting enough REquip so we decided to increase from 1.25 mg 3x a day to 2 mg 3x per day. And every two days increase the dosage by .50 3x a day. The doctor also noted an irregular heart beat and scheduled me for EKG and echo cardiogram on Monday. 12: AM took 2 mg of requip and sinemet 25/100 and 5mg of elderptyl 3 PM 1 25/100 sinemet 6 PM 1 25/100 sinemet 9 PM 1 sinemet and 2.00 mg of requip Days summary. My periods of on our increasing. I am taking sinemet 25/100 every three hours it takes a hour for the sinemet to kick in and turn Me on.( What a phrase.... it use to be inna tiney poka dot bikinis) I have then had 1 to 1 ¼ hours of on and off for the last 45 minutes of the dose. In retospect I felt super as I start the requip and then everything collapsed. I feel that occurred because it took a few days for the Parlodel to work out of my system and for those few days I was getting a boost from parlodel and requip. The requip did not come on line fast enough to replace parlodel. Beginning to feel better. Severance Manlius, NY