Hello everyone, After having been on pergolide (Permax) for sever= al years, and never having been convinced that it was actually doing anyt= hing, I asked my neuro if I could try Cabaser. He agreed, and three weeks= after starting it the difference is remarkable. "On" times have increased on average by 25%, "Kick-in" time for the Madop= ar is between 20 and 30 minutes and is much smoother than before, and eve= n in my "off" spells I am more mobile than before. I know that it is early days, and that nothing is guaranteed to last, but= it is a pleasure to be able to report something positive. Best Wishes Nigel. [log in to unmask]