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My mother Joyce (68/10 months) is slowly (very slowly) working her way up with Requip. She finds that within 1 hour of taking her dosage (which in some cases is low -- .25mg) she experiences a great deal of discomfort -- a tightness in the rib cage. Sometimes, taking aspirin seems to help. Does anyone else feel this?? (Tightness in the chest is something that's bothered her before Requip. She suspects it's drug related.) Debbie White [log in to unmask]