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Book Report (15 Jan 98) For current drug data, I used to buy the revised Physician's Desk Reference (PDR) every year, but it doesn't go out of date that fast, and this time I waited three years to get the 1998 edition. The PDR is the sovereign authority on drugs in the US, with (voluntary) contributions by makers of every prescription drug and many over-the-counter drugs. Unfortunately, many writers don't know the word "brief" and tend to drone on and on. Despite thin paper and tiny type, this makes the PDR a 3-inch-thick, 3200-plus-page, 7.5-pound whopper that is hard to handle, so as a rainy-day project I looked up page numbers for several of the drugs I see more often in my reading, and will stick this list inside the back cover. Too bad, the drugs approved last year didn't quite get into the 1998 edition; but if you buy one anyway, look for a sizable discount from the standard $75 price. Cheers, Joe Page Generic Brand# Use in PD treatment@ --* Acetazolamide (Diamox) Menstrual fluctuations of PD 2656 Albuterol (Proventil) Inhalant for bronchospasm (asthma) 916 Amantadine (Symmetrel) Antiviral, NMDA inhibitor -- Apomorphine ? Potent short-acting DA agonist 1612 Benztropine (Cogentin) Anticholinergic 1347 Biperiden (Akineton) Anticholinergic 1890 Bromocriptine (Parlodel) Postsynaptic DA agonist 2265 Cabergoline (Dostinex) Long-acting D2 agonist 1834 Clozapine (Clozaril) Tricyclic antipsychotic 1227 Desipramine (Norpramine) Tricyclic antidepressant -- Entacapone ? COMT inhibitor 2479 Levodopa (Larodopa) DA replenishment 874 L'dopa/C'dopa (Sinemet) DA replenishment -- Lisuride (Revanil) DA agonist (seldom used now) 2851 Paroxetine (Paxil) SSRI antidepressant 589 Pergolide (Permax) DA agonist -- Pramipexole (Mirapex) DA agonist (photos, but no text) 3075 Primidone (Mysoline) Anti-tremor 1042 Procyclidine (Kemadrin) Antispasmodic, for PD rigidity 3046 Propranolol (Inderal) Beta-blocker, anti-tremor -- Ropinirole (Requip) DA agonist 2897 Selegiline (Eldepryl) MAO-B inhibitor, DA agonist? 2229 Sertraline (Zoloft) SSRI antidepressant -- Tolcapone (Tasmar) COMT inhibitor 1388 Trihexyphenidyl(Artane) Antispasmodic, for rigidity # (May have more brand names, depending on maker and where sold) @ (Some data from non-PDR sources) * (Listed in PDR For Ophthalmology) J. R. Bruman (818) 789-3694 3527 Cody Road Sherman Oaks, CA 91403-5013