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Hello Everyone, As I had mentioned before, my father had been started on a trial of one of the newer PD meds, unfortunately without much success. Our feeling was, as with so many other treatments he's had over the years, "he just didn't give it enough time." Claimed it made him worse. Perhaps it did; who are we to argue with someone who obviously knows better than anyone else how he's feeling? In any case... I understand that in the last year there have been *4* (four) new drugs that have come online -- I've been seeing a lot of discussion here about Mirapex and Requip; are these 2 of these new meds? I can't recall what it was my dad was started on -- I think it was in early Spring 97, and at least 2 of these new meds had not come on the market yet -- But I don't think it would've been Requip, which to my understanding is for patients with early symptoms. My father's condition is quite advanced. I'm afraid it seems the only medication he's *ever* realized any significant benefit from is his Sinemet. As it is now, he wants to be taking it almost habitually -- almost like an addiction. Because it *does* help him feel better, for about 90 minutes at a streach. (After a 45-minute lag time, of course!) Thus, I'm afraid his quality of life is just miserable; it's like he's living for his next dose of Sinemet! It would be just wonderful if a medication were now available which could supplement and enhance the benefit he recieves from his Sinemet! Is this wishful thinking? Is there one of these "new drugs" available that will do that -- without all sorts of miserable side effects? I should note, I am more than 300 miles away, so any info I pick up here I have to pass along to him and my mom... It would be neat if I could print them up a run-down of the newer medications available, and provide that for them to review at their convienence. If anyone could lay a concise, clear listing of these meds and their actions/indications/ potential side effects on me, it would be *most* appreciated!!! Thanx! Stay Healthy! Roger