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I think it would be great to compile lists of supplements and their negative and/or positive reactions to pd. I know for a fact that when my husband runs out of pycnogenol or cellguard or liquid deprenyl he goes downhill. Now he's taking nadh again and it is also making a big difference. He takes many supplements and it would be nice to know which ones REALLY REALLY help and which ones do nothing much. As far as fear, if they have helped what is there to be afraid of? Den