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Jim, By mistake I think you have reinforced what some (at least myself) suspect. That if you truly follow your schedule and not become impatient (no pun intended) you don't necessarilly need a boatload of Sinemet. Post-Pallidotomy I was taking 1600 mg of Sinemet a day, until we tried replacing parlodel with mirape. I have cut Sinemet to 800 mg and think I possible could go further. The agonist seems to be the key. At least that is what I'm feeling. Good Day Mate, Greg Leeman [log in to unmask] -----Original Message----- From: Jim Cordy <[log in to unmask]> To: Multiple recipients of list PARKINSN <[log in to unmask]> Date: Sunday, January 25, 1998 6:01 AM Subject: requip: another data point >feeling the stress of giving birth to the Parkinson Alliance, I was counting >out the pile of pills I take daily, and casually popped into my mouth and >swallowed my full days quanity of Requip all at once. (18mg vs the 6mg three >times a day) I stood there with a dazed look on my face. My wife said what's >the matter? I told her. Panic for the next 30 minutes while we tried to get >a hold of a neurologist. > >Thank God for Ira Shoulson who has come to my rescue twice in recent months. >I believe he has a sincere appreciation for what I and that merry band of >advocates are doing to increase funding for Parkinson's research funding. I >know I have a sincere appreciation of what a caring physician Ira Shoulson >is. > > At any rate he returned my panicked Saturday morning call and went over >the likely consequences. I was put under the strict care and watchful eye >of my loving wife. Took it easy all day and suffered no ill effects. In >fact I did not take any Sinemet all day and discovered these agonists really >work. >Jim Cordy >Pittsburgh >[log in to unmask] >