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Hi Mario I got fed up with waiting for appointments with my neuro, so started modifying my own drug regime. I found: 1. In general, it worked OK so long as I didn't make any major or hasty changes: softly, softly catchee monkey! 2. some of the drugs seem to have a cumulative effect, in that they only appear to really start working after you have given them a few weeks to build up in the body. 3. It is equally as important to wind down slowly with a drug you are reducing, as ta wini up slowly when you are increasing. Because drug regimes are: a. so individual b. so potentially dangerous if mishandled I am not prepared to give more detail. For example, at a time when I was trying to reduce my Pergolide, a friend had been overdosed on it, and tried to commit suicide three or more times! My pharmaceutical knowledge is insufficient to say whether that was a direct cause and effect, or only part of a much more complex situation! Jeremy >I have been taking : ELDEPRYl-SYNNEMET-MIRAPEX 3 times a day. The last >time I went to the NEURO he suggested I stop taking SYNNEMET at night, >wait a week, then stop taking it in the afternoon. > >Today I stopped taking it in the morning. Also, last night I "forgot" >to take the MIRAPEX at night, and tonight it seems I am going to >"forget" also. > >Question: What I am doing - is it bad ? Am I playing russian roulette? >have not felt any adverse effects. I am following the precepts of my >Neuro who says less is better. Should I consult with him before doing >any of this stuff, or should I follow the dictates of my body and do >what feels appropriate and safe and keep an eye for any side effects? > >Anyone with similar experiences? I would like to hear from the list, >please. > >Thanks, > >Mario A. Gonzalez [log in to unmask] 51/2 > -- Jeremy Browne - [log in to unmask] Hampshire, UK