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> ---------- > From: Stephan Schwartz[SMTP:[log in to unmask]] > Reply To: Parkinson's Information Exchange > Sent: Thursday, January 29, 1998 7:01 AM > To: Multiple recipients of list PARKINSN > Subject: Re: NEW GENE? -Reply > > Jim wrote: > >>> Jim Slattery <[log in to unmask]> 01/28/98 05:37pm >>> > >Clinton last nite claimed " a gene has been found that > causes > >Parkinson." Fact or new lie?< > >>>A search of the Medline research paper database shows > no new gene links to PD. There was a familial gene > connection shown in one Italian study of one family, and > another is Spain. However, most of the /PD gene studies to > date (over 600) show no differences between PD sufferers > and non-PD controls.<<< > >>>Wishful thinking, or a 'white lie' to promote support for > the NIS appropriation bill?<<< > ----------------------------------------- > Jim Slattery - [log in to unmask] > CW PD Web - [log in to unmask] > http://www.bec.net.au/~cwpdg/ > ------------------------------------------ > Jim: > > At the National Center for Human Gene Research > [NCHGR] a team led by Dr. Roger Duvoisin announced in > January 1997 that they had " . . .identified the gene > responsible for Parkinson's disease in the Contursi family. . " > in a study covering eleven generations of that family both in > Italy and America. This team also claimed they had found > the ". . . same gene . . . " in three other unrelated family > groups of Greek origin. > The disease may be caused by the absence of a protein > or the existence of a toxic protein called "alpha-synuclein." > The researchers caution that not all Parkinson's disease is > explained by this abnormal protein, probably only a small > portion of the family-related disease. > Now the researchers must establish a connection > between this abnormal protein and the death (apoptosis) of > brain cells. > > Stephan 53/7 >