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Hi Jan, Glad I could help a little! I'm guessing the neuro is not a PD or Movement Disorder specialist 'cause one of them would have been more likely to know about decreasing the sinemet with mirapex (YES that's usually done to avoid serious overdose-type side effects). Lemme see if I can figure out our new system for looking up stuff in the archives, and I'll get back to you with any dosage details I find. Mary