In a message dated 98-02-06 01:15:53 EST, you write: << My sister has chronic fatigue and is currently taking b-12 shots twice a week. She claims that they increase her energy level significantly. I've had PD for over 15 years and during much of that time fatigue has been a major problem for me . I wonder if these shots could offer some relief for me? Has anyone out there any experience with b-12 shots? I would be interested in any information you might have. Steve Evans 48/16 >> My husband's neurologist told him a lack of B-12 hs a different meaning to a neurologist than to other doctors. My husband tested low in B-12 and after a battle with our internist instituted a series of B-12 shots to bring him up to speed. He now has a shot once a week or every other week. It made a great difference to him, from being terribly tired all the time to being able to function much better. Hope it works for you. Dealing with Parkinsons is enough to wear anyone out and all help is needed. Virginia [log in to unmask]