> CURRENT SCIENCE REVIEWS By Joe Bruman February 1998 Page 1 of 3
> Beijjani B et al; Neur 1997;49:1564-1569:
> The probe used for Deep-Brain Stimulation (DBS) has a choice of four
> stimulation sites along its length, allowing a comparison after the
> implantation is complete. Stimulation at the top (dorsal) surface of
> the pallidum had effect strikingly different from stimulation at the
> lower (posteroventral) surface. Current functional models of the
> basal ganglia don't explain paradoxical effects of either pallidotomy
> or DBS; for example, how levodopa-induced dyskinesia (LID) can be
> suppressed simultaneously with improvement of classic PD signs; and
> authors suggest maybe different neuroanatomic systems are involved.
>
Hi Joe
Good summary of the evidence for an alternative view of PD .
peace
Alastair ( [log in to unmask] )
