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On Sun, 8 Feb 1998 11:51:30 -0500, JG <[log in to unmask]> wrote, in part: > Does anyone take sinemet throughout the night in order to sleep? If so, > does anyone know if this is a bad thing to do? Bob has been doing this > for about six weeks and during his off time his disease if much worse. > Initally, it put him to sleep for about 3.5 hours, now 1.0 hour. So, he > is going to try to discontinue this, even tho it puts him to sleep like > a baby. Unfortunately, he can't sleep unless he is 'on'. Hi Jackie - Mom (64/22) also takes Sinemet at night for sleep. She takes a 50/200 CR every 4 hours day and night, supplemented by 1/2 of a 25/100 regular 3 to 4 times a day. Mom has tried skipping the 2:00am dose if she's asleep when the time comes, but when she does that she tends to wake up "off" and that it takes a lot of effort to get her equilibrium back. I think waking up for the dose works better for her, but as we all know every case is different. Good luck with your situation. - Doug [log in to unmask]