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I had been up to 7 mg/day of mirapex(prescribed by Dr. Goetz - head of the Movement disorders program at Rush-Presbyterian in Chicago ) but it didn't help so we switched to Requip. I am now at 20mg/day (maximum suggested dose 24 mg/day) and I have improved. It is not uncommon at all to go above the FDA maximum suggested doses as long as you tell the patient that you are doing it and he/she agrees. Wording in the package insert is slightly different. Usually these drugs say safety and/or efficacy has not been established where when it is an established maximum dose it will say doses above x mg are not recommended. If there is an established safety concern it will be noted in the insert. Good luck Charlie Allan Rosenberg wrote: > > The literature we had originally from the manufacturer recommended dosages up > to 4.5mg. Our neurologist says many people have gone as high as 6.0mg with > good results if they can tolerate it. Has anyone any experience at dosages > over 4.5 ? > > Allanros -- CHARLES T. MEYER, M.D. Middleton, WI [log in to unmask]