Hi Brian Collins wrote: >I also find it best to take a single Madopar CR 25/100 just > befire I go to sleep: it is relaxing , but does not set my mind ticking > over too fast as a full dose would do (Its about half a daytime dose) and later: > Madopar is a different trade name containing levodopa, and is available > in UK, Canada, France, and maybe other countries. I don't recommend one >as being better than the other, I use a Sinemet 25/100 in exactly the same way (ie as a means of relaxing enough to fall asleep). Incidently, harking back to an earlier thread, since starting this practice some months ago I have started to dream again. But, to get back on track, here in Australia levodopa is available as both Sinemet (levodopa + carbidopa) and Madopar (levodopa + benserazide). I have at times used each of them and, with the exception of their slow release versions, found that each worked equally well for me. For a period I was taking a madopar Q (50g levodopa/12.5 benserazide) together with a sinemet CR (slow release/200g levodopa/50g ). Eventually the madopar Q was replaced by 1/2 a sinemet (25/100). I noticed no differences in their effects on me. Of course my observations are both subjective and anecdotal. As already stated the only difference I have found was in my reaction to their slow release versions ie madopar HBS and sinemet CR, and I believe this resulted from the different mechanisms by which each achieves slow release rather than from their respective use of benserazide and carbidopa. Dennis. ************************************************** Dennis Greene 48/11 [log in to unmask] http://members.networx.net.au/~dennisg/ **************************************************