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I have two observations of things that seem to work for me and may help others. It seems my tremor is worse in bed and sometimes wakens me about 4-5 hours after my last dose of meds, 1/2 Sinemet 50/200, at bedtime. As a leftie, that's where the tremor occurs. I can usually stop it by bending my left thumb into my palm and holding it with my fingers. Don't know what sense that makes but there's a lot of things about PD that don't. I sometimes have been wakened by restless legs and after moving them around until my patience runs out, I usually find I can get to sleep on my stomach with my head turned to the right. Hardly medically proven observations but they seem work, for me. Don of W. PA. [log in to unmask]