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Just came across this on the CNN website
(http://www.cnn.com/HEALTH/9802/09/antihistamine.reut/)

In particular, note the potential for trouble when using hismanal with
prozac etc.

(sorry about the weird spacing)

Mary Rack
[log in to unmask]

"The new labeling provides information about a specific warning
                     against simultaneously using Hismanal with other
types of drugs
                     such as the hypertension drug Posicor (mibefradil)
and the
                     antibiotics Biaxin (clarithromycin) and TAO
(troleandomycin)."

                     Other drugs Hismanal should not be taken with
include HIV
                     protease inhibitor drugs such as Crixivan
(indinavir), Norvir
                     (ritonavir) and Viracept (nelfinavir),
anti-depressants in the SSRI
                     class such as Prozac, known generically as
fluoxetine, Zoloft or
                     sertraline, and Paxil or paroxetine.

                     It should also not be combined with Zyflo or
zileuton, an asthma
                     drug, or with grapefruit juice, which is known to
make some drugs
                     act more effectively in the body.