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Marling McReynolds wrote:

> ... doctors seems to prescribe larger than needed doses for first
> time users, especially of sinemet.  ....  I was on 50/200 every 4
> hours in the beginning

Sounds like a lot.  How bad was your beginning?  What were your
symptoms a that time?

> and after the initial good reaction (sinemet certainly controls the
> pd symptoms) I experienced the worst of side-effects.  Now I am on
> the least of sinemet cr (25/100) and only take it at my worst time
> of day, with requip the rest of the time

It was true in my case with my first doc - a general neurologist.
Problem is, in the beginning we may tolerate overdoses fairly well,
and also be unaware of the differences between disease symptoms and
medicine side effects, so we don't know what's an overdose.

Now I'm at a point where the difference between too little sinemet
and too much is narrowing.  There are not enough gradations in size
of available doses.   25/100 can be too little and 50/200 too
much.

Phil Tompkins
Hoboken NJ
60/9