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HI DALE- By wearing off are you talking about end dose loss of effectiveness or are you talking about the development of tolerance- the loss of overall effectiveness? I do think that I have lost a little of the gains I have experienced as time has gone on and I have remained on the same dose. Charlie Dale Severance wrote: > > I quess you can see from my messages that I am wired up this morning. > > Several weeks ago a few comments were made on the net > about requip wearing off. At that time I asked requip salesman what he had > heard on that subject. I advised the list that he reported no notice of such a > problem. > > I learned yesterday that several manufacture's repre's are meeting with my > doctor to discuss this very issue. Apparently the wearing off effect is > beginning to get the manufactures attention. I personally am slipping back > from my original requip level and I have been on requip about three months > now. > > Dale Severance -- CHARLES T. MEYER, M.D. Middleton, WI [log in to unmask]