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Dear Members, Does anyone take sinemet throughout the night in order to sleep? If so, does anyone know if this is a bad thing to do? Bob has been doing this for about six weeks and during his off time his disease if much worse. Initally, it put him to sleep for about 3.5 hours, now 1.0 hour. So, he is going to try to discontinue this, even tho it puts him to sleep like a baby. Unfortunately, he can't sleep unless he is 'on'. Ida --- your post really hit home, Bob paces the floor all the time, sometimes for hours, he says it seems to provide some relief or escape from pain, burning sensation in arms and legs, and from a aching, pain, pressure feeling. It subsides when he CANwalk, but immediately, upon sitting, all of the horrible feelings return. Currently Bob is taking: 10/100 reg. sinemet (two) every 2.5 hours; one 20 mg. paxil in the evening; twice a day, one 25/100 CR. Thanks for all of your help and for listening. Jackie for Bob, 47 - 7yrs.