After three days I have penetrated the golden doors of Parkinsn no I haven't discovered what we are all hoping for but managed to get accepted to your group. hello I am Margaret Clark aged 59 diagnosed with PD nearly 10 years ago. Have been lucky it has progressed slowly but just am feeling that things are realy taking hold. I have spent 4 months graduating from Permax to the new Mirapex. Have a great difficulty with getting all medications balanced with still an on off period.along with all the well known symptoms plus i have developed a noticable scoliosis Itake 4 `/2 Mirapex 4 sinemet cr50/2001 1 1/2 sinemet 25/100 2 elderpryl 2000 units Vit E per Day am still able to drive but do not work. I am investigating into the toxic effect of house gas that I was exposed to in 1966.Would like to hear from anyone with PD and similiar background history. Hope you all have agood positive day Margaret