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Alastair, I hope you don't mend me jumping into this discussion, but I don't want to forget a thought about your theory. You seem to be knowlegeable about electronics. There are two technologies that might be adaptable to the fight against PD and similar conditions. The first involves what is done by an equalizer in a sound system, where weak parts of the wave form, such as bass notes are amplified more than strong ones, to result in a balanced output across the audio spectrum, to make the sound as close to the original performance as possible to the ear. The other one is the use of a microphone in front of a speaker, which delivers samples of the sound coming from the speaker to correct distortion. If the speaker is sending out too much power at a particular frequency, the electronic circuits compensate and reduce the power reciprocally, to result in a more perfect replica of the original sound. I realize my explanation not be accurate, and my understanding cloudy. IF the electrons or neurons firing in the affected part of the brain could be monitored and corrected, as is done with heart pacemaker systems, it might work to automatically stop the symptoms. The stimulation that is done now, as far as I can understand, is just a manually controlled signal from the outside without feedback from the brain. Tell me if I am correct. Also if you think I am onto something. [log in to unmask]