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^^^^^^WARM GREETINGS FROM^^^^^^^^^^ Ivan Suzman 48/10 [log in to unmask] Portland, Maine land of lighthouses 40 deg. Fmelting snow *********************************************************** Dear Brian, Stefan, Dennis, Ron, Linda and Gail, Linda Corson asks: "... my basic nuts-n-bolts questions are: 1. What's the minimum daily carbidopa level for the levodopa to be maximally effective? 2. What are the side-effects of too much carbidopa? 3. At what level do the side-effects typically start to app ear?" I am especially interested in questions 2 and 3 and would like to share any insights with my monthly support group. It meets tomorrow afternoon. I also would like to add another question to the fascinating carbidopa/levodopa discussion occurring on the list. My "kick-in" time for Carbidopa/levodopa 25/100 is about 35 minutes, with some variations. QUESTION: Would a 10/100 pill kick in at the same rate? I am wondering how the c-dopa/l-dopa ratios (1/4 and 1/10) influence a PWP's dosing schedule. Thanks, Ivan