^^^^^^WARM GREETINGS FROM^^^^^^^^^^ Ivan Suzman 48/10 [log in to unmask] Portland, Maine land of lighthouses 32 deg. F *********************************************************** Good morning from Portland, Maine, friends on the List, On Tue, 17 Feb 1998 10:05:33 -0500 "Corson, Linda" [log in to unmask] writes about her dad, Bill: "Dear Listfriends / Cyberfamily- " I remember Alan Bonander giving an eloquent presentation on the need to keep carbidopa intake below 200mg per day, but I don't recall the side effects of too much carbidopa...." <SNIP> Linda bravely continues, in reference to his hallucinations: ".... If adjusting his PD meds can make his final days a bit more clear-headed...." <SNIP> I believe that the "quality of life," for MILLIONS of us PWP's (people with Parkinson's), and our care-providing families and friends, might be vastly improved if we understood how to regulate CARBIDOPA levels in our bloodstreams. In the United States alone, we have many different options offered to us, by using combinations of at least 4 different carbidopa/levodopa pills (for example, blue 10/100's, pink football-shaped: 25/100 CR's {continuous release} , yellow 25/100's and cafe-au-lait, or coffee-colored, football-shaped 50/200 CR's). I would like to expand on Linda's question about her dad, and identify 7 common, troubling, SPECIFIC side-effects. Some of these have been mentioned in the last few weeks of our correspondence on our List. The 7 peak-dose side-effects (P) or end-of-dose side-effects (E) are: END of DOSE: (E1) the end-of-dose sweats, (E2) the rapid tremors (Marling's "internal whim-whams" / Ida's "cold turkey"), (E3) the freezing spells( sudden lack of movement), (E4) the sudden feeling of cold (my "hypothermia"), and pain in the shins, feet, toes and hands and fingers. PEAK DOSE: (P1) sweats (P2) hallucinations (like BIll's) (P3) abnormal movements (dyskinesias) Would ANYONE be able to share ideas on the problems caused specifically by either too high, or too low, circulating CARBIDOPA levels, and the associated Sinemet and Madopar pill strengths? Ivan Suzman 48/10