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The range of blood pressure can be quite scary. My husband 81/9 has had it go from 200 to under 100 in a short time. First of all sinemet does affect the bp also a meal will lower the bp. It takes an hour before it comes back, however, when it goes to 75/40 that is not good and immediate action needs to be taken . What I do is get him on the floor or bed with his feet elevated and give him some chicken boulion (sp?) or for a quicker return a small bit of straight salt followed by water. The low bps are dangerous because the blood is not getting to the brain. I can watch him eat a meal, be fine and before my eyes watch the change in him as the bp goes down There are some medications available, but do have some side affects. Hope this helps. I find that many drs. are not aware of the wide swings in a short time that can occur. [log in to unmask] Los Angeles, CA