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Marling: My sincere appreciation. I KNEW if I just kept it up, sooner or later, knowing THIS group, someone would quit having mercy on me and ARGUE with me. I'll just say quickly, (and give it a thoughtier response later), that anyone who has sensitivities in their family knows this much: There is NOTHING MORE INDIVIDUALIZED than people's sensitivities and the TYPES OF REACTIONS they have. They do seem to be CUSTOM MADE for each person. The age question is answered in "My Story"- the older we get the more likely we are to become HYPERSENSITIVE, because, by virtue of our age we have had much more exposure to any potential allergens. And, I repeat, it is a PROVEN FACT that there are MANY causes of Parkinsonian symptoms, I'm suggesting ONE MORE. As we simplify equations and fractions in order to make it easier to understand and solve the problem, would it be okay for the same purposes to simplify the terms we use for this discussion? I suggest instead of allergies - histamine - which brings it closer to the real meaning. Instead of Parkinson's Disease - Parkinsonian symptoms - because - if you will take ALL the symptoms and I NEVER have to have any, then I'll take the DISEASE. I realize that is not always true for every disease, but in most instances we are closer to what we are really dealing with, and have LESS prejudicial PREFORMED OPINIONS about a group of symptoms. It allows us perhaps to consider something afresh, AND FROM a different perspective, in other words, we are OPEN to LEARN, if we don't already think we KNOW all about it. As an example of how we get "set in our ways" with our thinking, everybody does, my husband, the math major & programmer, was explaining to our son that we use base 10 in math usually, but computers usually use base 16 (I think) because of the 0,1 thing, (okay you guys help me out) WHATEVER, anyway he did some simple addition in some different bases and it BLOWS my mind, 1+1 IS NOT 2 sometimes. I'll just leave it to them and stick with my ten fingers & toes... Or we could call it Dopamine Deficiency Disorder, which Dr. Leiberman I believe calls it, in which case we wouldn't be PWP but 3D. Sounds better, and is much closer to the true meaning. Histamine then is a chemical like dopamine that EVERYONE has in their body, but people with allergies have BOO-KOOs MORE usually because histamine (and actually other chemicals too) are released open exposure to something they are sensitive to. Although, if you see the research that I cited, ANYONE, who has an initializing event (frozen shoulder???maybe, tumor, etc.) that would cause an ischemic condition, it would seem that perhaps that might kick off a vicious every worsening cycle in ANYONE??? (This is PURE QUESTION, not even THEORY). It would go like this maybe, Initializing event causing ischemia,=ischemia induced rise in histamine=neck muscle spasm= more ischemia=more histamine=less dopamine=need more Sinemet= less getting through=progression???????? Just a wild thought. Maybe not TOO wild?? And just to introduce some more fuel to the fire- histamine causes MUSCLE SPASM (as in bronchospasm/asthma) and has anyone else noticed how many of our 3D symptoms are located in the NECK? The NECK was what I massaged for a long time in severe suffering and all-of-a-sudden the whole SCHMASH of 3D symptoms (tremor, bradykinesia, rigidity) WENT AWAY. The NECK is particularly fragile, a small conduit for a number of VITAL things. THE REASON as we all know for THE HANGMAN'S NOOSE, the MURDERER'S LIGATURE-just a drapery cord or a length of just about anything, or just the MURDERER'S GLOVED HANDS (2 sizes too small, natch). Our NECK symptoms include (VOICE (larnyx) problems, swallowing problems ie esophageal reflux, I've had breathing problems at times, the CRUCIAL circulatory connections from body to brain, Shy-Drager patients die of LARYNGEAL STRIDOR many times (stridor refers to the high-pitched sound),I believe PD patients many times die of pneumonia, which can be caused by aspirating food or something else into the lungs.....comments?? Imagine the sequence of events if you would gradually TIGHTEN DOWN on someone's neck with your hands, ... voice problems, swallowing problems, breathing problems,gradually cutting of blood supply to brain would begin to cause mental problems, confusion, disorientation, syncope (fainting),and if you wouldn't quit-death by strangulation. Also, the symptoms that HISTAMINE can cause, as I've mentioned include symptoms of ANAPHYLAXIS which includes a myriad of symptoms since it is a MULTIPLE SYSTEM, WHOLE BODY, SYSTEMIC, reaction. Mental symptoms, digestive symptoms (the reason that two of my friend's fathers w/PD died- they quit eating-seemingly starved) I've been down to BABY FOOD because my digestive system was SHUTTING DOWN. It's an intuitive reaction, not a willful stubborn refusal to eat. It seems we intuitively take the same route foodwise- leaving off food in order of its difficulty to digest- First- meat, then fat, dairly products, sweets, then breads & grains, till we're down to fruits & vegs, then baby food, THEN IV's???? Mental problems, agitation, confusion, lethargy, somnolence, as I have said. Heart problems, arrhythmias, skin rashes, incontinence, low blood pressure, shock, your WHOLE BODY is reacting. Just some FOOD FOR THOUGHT. How does the LAMEBRAIN theory explain these. If it's because MORE & MORE portions of the BRAIN are DYING, I must have a vacant cranium, if so, how did it as a child might ask, UNDEAD itself?????? Comments, corrections, additions?????? Still a heretic, Janet [log in to unmask] BTW Marling I, even if I am the ONLY one,I think that your brilliant brain is probably still intact, and not LAME, as we all are told.