My wife (54/4) is taking a significant amount of medication an increasingly more frequent intervals. Every 1 3/4 hours (one and three quarters hours) she takes 1 Sinemet 25/100, 2 Sinemet CR 25/100 and 3/8 or 3/4 mg Mirapex. Somewhat less often when she is sleeping. Has anyone had experience with these levels of usage? Jeff Heyser ([log in to unmask])